1. Medicinal Chemist/Associate Scientist on one of our drug discovery programs

As a successful candidate you are responsible for the medicinal chemistry aspects of our main drug discovery project and will be driving the development of novel drug discovery programs. You are able to design molecules, their synthesis pathways and quality control and you are able to generate and interpret relevant DMPK data, all mostly by means of interactions with CROs.

You are experienced in using this data to iteratively design better molecules, solve DMPK issues and generally steer compound development programs towards success. You excel in working in a structured way, you can manage and organize large amounts of data in ways that ensure IP protection, smooth information exchange and gaining high-level overviews and you are comfortable with presenting medicinal chemistry information to multi-disciplinary teams.

You have experience in drug discovery programs, preferably in a commercial setting.

As a successful candidate you have a strong self-drive and you are able to set and plan tight timelines and budgets. Experience in the very early steps of the discovery pipeline, i.e. assay development and high-throughput screening is considered a pre.

Responsibilities and abilities
• You are the driving force behind development of chemical matter in drug discovery programs, maintain the overview and actively interact with all contributors to that project;
• Responsible for initiating and managing a wide array of DMPK activities and in vitro and in vivo validation efforts;
• You engage with Contract Research Organizations (CRO’s) to setup research projects and monitor and manage their work, analyze the results and propose next steps;
• Combine expert chemical, biological and technical knowledge and research expertise that can be leveraged to drive existing projects, but you can also initiate novel research avenues;
• You generate regular reports on project progress, including timelines and budget implications in case of project deviations;
• Generation of figures, slide decks and reports for internal and external use.

Qualifications and experience
• PhD in relevant subject with 3+ years postdoctoral experience in a research environment;
• Extensive expertise in one or several of the following areas: biochemistry and medicinal chemistry, DMPK, animal modelling, HTS campaigns;
• 3+ years of experience in Biotech/Pharma or related commercial environment;
• Broad understanding of cellular disease mechanisms;
• Proven track record of success and creativity, for instance having high impact first author publication(s) and/or patent(s);
• Experience with the outsourcing of research activities is an advantage as is knowledge and experience with protecting IP surrounding small molecule programs.

Personal qualities
• Considerable tenacity, energy and drive, self-motivated and capable of setting your own targets;
• Excellent analytical and data management skills combined with a creative problem-solving mindset;
• Attention for detail and high experimental and scientific standards;
• Broad interest and flexibility to work on diverse biological topics relevant to human disease;
• Affinity to work in a start-up, which means being flexible, being able to deal with uncertainty and work and thrive in a highly dynamic environment;
• Team player with excellent interpersonal and communication skills with great command of English, written and spoken. Dutch not required;
• Excellent time management skills.

We offer
• Employment for 32-40 hours/week;
• A stimulating environment with the opportunity to be part of an enthusiastic team that together is building the company from the ground up;
• The possibility to contribute to the development of novel therapeutic products for patients;
• A competitive remuneration package, including sharing in the success of the company, and attention for personal development.

Are you our new team member?
If this vacancy is the perfect next step in your career, please send your resume and cover letter before September 1, 2020 to jobs@scenicbiotech.com attn. Carola Jongerius (HR Manager) or click on ‘Jump in’! Please mention the number of this vacancy (no.1) in your application.

Applications without cover letter will not be processed.